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The AE1 monoclonal antibody recognizes 56.5, 54', 50, 50’, 48, and 40kDa proteins (also known as CK10, 14, 15, 16 and 19) in mouse, human, rat, primate (cynomolgus and rhesus), dog, cat, rabbit and chicken.Description & Specifications
DescriptionThe monoclonal antibody AE1 recognizes many members of the acidic (Type I) family of cytokeratins. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an α-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these cytokeratins, and their expression can help identify the origin of a neoplasm.
The AE1 monoclonal antibody recognizes 56.5, 54', 50, 50’, 48, and 40kDa proteins (also known as CK10, 14, 15, 16 and 19) in mouse, human, rat, primate (cynomolgus and rhesus), dog, cat, rabbit and chicken.
|A20, Acidic Cytokeratin|
|Immunocytochemistry,Immunohistochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Western Blot|
|Store at 2-8°C.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|