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Tocris™ A 740003

Potent and selective P2X7 antagonist

$212.06 - $893.21

Specifications

Product Type A 740003
Inhibitors A 740003
Molecular Weight 474.55
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

370110R

 
tocris™
3701/10
10mg Each for $212.06

370150R

 
tocris™
3701/50
50mg Each for $893.21
Description & Specifications

Specifications

Product Type A 740003
Inhibitors A 740003
Molecular Weight 474.55
Purity >98

Potent and selective P2X7 receptor antagonist (IC50 values are 18 and 40nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100μM. Reduces nociception in animal models of persistent neuropathic and inflammatory pain. Also reduces neuroblastoma tumor growth in mice.

  • Chemical Name: N-[1-[[(Cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide
  • Formula: C26H30N6O3
  • CAS Number: 861393-28-4
  • Solubility: Soluble to 20mM in DMSO
  • Purity: >98