Please login to your online account to display your discounted pricing

Alfa Aesar™ 6,7-Dihydroxycoumarin, 98+%

$73.15 - $273.55

Chemical Identifiers

Chemical Name or Material 6,7-Dihydroxycoumarin
CAS 305-01-1
Molecular Formula C9H6O4
Formula Weight 178.15g/mol
MDL Number MFCD00006874
Beilstein 152788
Merck Index 14,3697
Synonym Cichorigenin; Esculetin
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA1539303

 
alfa aesar™
A15393-03
1g Each for $73.15

AAA1539306

 
alfa aesar™
A15393-06
5g Each for $273.55
Description & Specifications

Specifications

Melting Point ≈270°C (dec.)
Quantity 1g
Chemical Name or Material 6,7-Dihydroxycoumarin
CAS 305-01-1
Assay ≥98%
Molecular Formula C9H6O4
Formula Weight 178.15g/mol
MDL Number MFCD00006874
Beilstein 152788
Merck Index 14,3697
Synonym Cichorigenin; Esculetin
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage 2° to 8°C
RTECS Number GN6382500

Applications
In the presence of esculetin and HA14-1 (sc-205911) expression of the death receptor 4 (DR4) has been observed to be upregulated and extracellular-regulated kinase (ERK) to be activated. Other studies suggest that esculetin upregulates death receptor 5 (DR5) protein expression, and enhances TRAIL-induced apoptosis. It also inhibits the activity of 12-LO (12-lipoxygenase), and decreases leukotriene biosynthesis during 5-LO inhibition.

Solubility
Soluble in DMSO, DMF, diluted alkalies with blue fluorescence, and acetone. Slightly soluble in water. Insoluble in ether. Moderately soluble in Glacial acetic acid, and hot ethanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

2° to 8°C