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Alfa Aesar™ 6,7-Dihydroxycoumarin, 98+%

$73.43 - $261.68

Chemical Identifiers

CAS 305-01-1
Molecular Formula C9H6O4
Formula Weight 178.15
MDL Number MFCD00006874
Beilstein 152788
Merck Index 14,3697
Synonym Cichorigenin; Esculetin
Chemical Name or Material 6,7-Dihydroxycoumarin
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAA1539303 SDS Alfa Aesar™
A1539303
1g Each for $73.43
AAA1539306 SDS Alfa Aesar™
A1539306
5g Each for $261.68
Specifications

Description

Applications
In the presence of esculetin and HA14-1 (sc-205911) expression of the death receptor 4 (DR4) has been observed to be upregulated and extracellular-regulated kinase (ERK) to be activated. Other studies suggest that esculetin upregulates death receptor 5 (DR5) protein expression, and enhances TRAIL-induced apoptosis. It also inhibits the activity of 12-LO (12-lipoxygenase), and decreases leukotriene biosynthesis during 5-LO inhibition.

Solubility
Soluble in DMSO, DMF, diluted alkalies with blue fluorescence, and acetone. Slightly soluble in water. Insoluble in ether. Moderately soluble in Glacial acetic acid, and hot ethanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents.
Description & Specifications

Chemical Identifiers

305-01-1
178.15
152788
Cichorigenin; Esculetin
C9H6O4
MFCD00006874
14,3697
6,7-Dihydroxycoumarin

Specifications

≈270°C (dec.)
305-01-1
178.15
152788
Cichorigenin; Esculetin
≥98%
1g
C9H6O4
MFCD00006874
14,3697
6,7-Dihydroxycoumarin

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : GN6382500

Recommended Storage : 2° to 8°C