missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Alfa Aesar™ 6,7-Dihydroxycoumarin, 98+%

Manufacturer:  Alfa Aesar™ A1539303

 View more versions of this product

Catalog No. AAA1539303



Description

Description

Applications
In the presence of esculetin and HA14-1 (sc-205911) expression of the death receptor 4 (DR4) has been observed to be upregulated and extracellular-regulated kinase (ERK) to be activated. Other studies suggest that esculetin upregulates death receptor 5 (DR5) protein expression, and enhances TRAIL-induced apoptosis. It also inhibits the activity of 12-LO (12-lipoxygenase), and decreases leukotriene biosynthesis during 5-LO inhibition.

Solubility
Soluble in DMSO, DMF, diluted alkalies with blue fluorescence, and acetone. Slightly soluble in water. Insoluble in ether. Moderately soluble in Glacial acetic acid, and hot ethanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents.
Specifications

Specifications

6,7-Dihydroxycoumarin
1g
C9H6O4
152788
esculetin, 6,7-dihydroxycoumarin, aesculetin, cichorigenin, 6,7-dihydroxy-2h-chromen-2-one, cichoriin aglucon, esculatin, esculetol, esculin aglucon, esculin aglycon
C1=CC(=O)OC2=CC(=C(C=C21)O)O
178.143
CHEBI:490095
≥98%
~270°C (decomposition)
305-01-1
MFCD00006874
14,3697
ILEDWLMCKZNDJK-UHFFFAOYSA-N
6,7-dihydroxychromen-2-one
5281416
178.15

Chemical Identifiers

305-01-1
178.143
ILEDWLMCKZNDJK-UHFFFAOYSA-N
5281416
6,7-dihydroxychromen-2-one
C9H6O4
MFCD00006874
esculetin, 6,7-dihydroxycoumarin, aesculetin, cichorigenin, 6,7-dihydroxy-2h-chromen-2-one, cichoriin aglucon, esculatin, esculetol, esculin aglucon, esculin aglycon
CHEBI:490095
C1=CC(=O)OC2=CC(=C(C=C21)O)O
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : GN6382500

Recommended Storage : 2° to 8°C

Documents