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Thermo Scientific Chemicals 5-Fluorouracil, 99%
5-Fluorouracil, CAS # 51-21-8, is an analogue base composed of uracil with a position 5 hydrogen fluorine substitution.
Supplier: Thermo Scientific Chemicals 228440250
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• 5-Fluorouracil is an antimetabolite and antineoplastic that prevents DNA synthesis by blocking conversion of deoxyuridylic acid
• 5-Fluorouracil can replace uracil in RNA and prevent protein synthesis and cell growth
Applications
• 5-Fluorouracil can be used for laboratory research on tumor growth and immunosuppression
• 5-Fluorouracil may also be appropriate for laboratory studies of neurotoxicity, cell lysis, and DNA damage
Specifications
| 5-Fluorouracil | |
| 278.0°C to 282.0°C | |
| 190.0°C to 200.0°C (0.1 mmHg) | |
| Authentic | |
| Glass bottle | |
| MFCD00006018 | |
| 24,IV,1229 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 5-fluoro-1H-pyrimidine-2,4-dione | |
| 3385 | |
| 130.08 | |
| Crystalline Powder |
| 51-21-8 | |
| White | |
| 0.5% (80°C, 4 hrs) (in vacuum) max. | |
| 99% | |
| C4H3FN2O2 | |
| 25 g | |
| 15,4213 | |
| Solubility in water: 12.2g/L (20°C). Other solubilities: 2.9g/L (20°C) in ethanol,readily soluble in aqueous alkali solutions,soluble in dmso | |
| FC1=CNC(=O)NC1=O | |
| 130.08 | |
| CHEBI:46345 | |
| 99% |
Chemical Identifiers
| 51-21-8 | |
| 130.08 | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 3385 | |
| 5-fluoro-1H-pyrimidine-2,4-dione |
| C4H3FN2O2 | |
| MFCD00006018 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| CHEBI:46345 | |
| FC1=CNC(=O)NC1=O |
Safety and Handling
GHS H Statement
Suspected of causing genetic defects.
Suspected of damaging the unborn child.
Toxic if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Causes serious eye irritation.
Causes skin irri
GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF INHALED: Remove victim to fresh air and keep at rest in a position comforta
GHS Signal Word: Danger
EINECSNumber : 200-085-6
RUO – Research Use Only