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Alfa Aesar™ 5-Fluorouracil, 99%

Chemical Identifiers

Chemical Name or Material 5-Fluorouracil
CAS 51-21-8
Molecular Formula C4H3FN2O2
Formula Weight 130.08g/mol
MDL Number MFCD00006018
UN Number UN2811
Beilstein 127172
Merck Index 14,4181
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAA1345606

 
alfa aesar
A13456-06
5g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAA1345614

 
alfa aesar™
A13456-14
25g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAA1345622

 
alfa aesar™
A13456-22
100g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Quantity 5g
Chemical Name or Material 5-Fluorouracil
CAS 51-21-8
Assay 99%
Assay Percent Range 99%
Molecular Formula C4H3FN2O2
Formula Weight 130.08g/mol
MDL Number MFCD00006018
UN Number UN2811
Beilstein 127172
Merck Index 14,4181
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H360-H341-H373-H302
May damage fertility or the unborn child.
Suspected of causing genetic defects.
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
Health Hazard 3 GHS P Statement
P260-P281-P301+P312-P308+P313-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
Use personal protective equipment as required.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
I
Storage Note 1 Air Sensitive
DOT Information Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
RTECS Number YR0350000
TSCA TSCA

Applications
5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen′s disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor.

Solubility
Soluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.

Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.

Safety and Handling

Danger

GHS P Statement
P260-P281-P301+P312-P308+P313-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
Use personal protective equipment as required.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
I

GHS H Statement
H360-H341-H373-H302
May damage fertility or the unborn child.
Suspected of causing genetic defects.
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.

Air Sensitive