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5-Fluorouracil, 99%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A1345614
Description
5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen's disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.
Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
Specifications
| 5-Fluorouracil | |
| ∼282°C (decomposition) | |
| C4H3FN2O2 | |
| 25 g | |
| 127172 | |
| 14,4181 | |
| Soluble in dimethylformamide,dimethyl sulfoxide,methanol,hot water,ammonium hydroxide,sodium hydroxide,ethanol and water. | |
| FC1=CNC(=O)NC1=O | |
| 130.08 | |
| CHEBI:46345 | |
| 99% |
| 51-21-8 | |
| 99% | |
| MFCD00006018 | |
| UN2811 | |
| Light sensitive | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 5-fluoro-1H-pyrimidine-2,4-dione | |
| 3385 | |
| 130.08 |
Chemical Identifiers
| 51-21-8 | |
| 130.08 | |
| GHASVSINZRGABV-UHFFFAOYSA-N | |
| 3385 | |
| 5-fluoro-1H-pyrimidine-2,4-dione |
| C4H3FN2O2 | |
| MFCD00006018 | |
| 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton | |
| CHEBI:46345 | |
| FC1=CNC(=O)NC1=O |
Safety and Handling
GHS H Statement
H360-H341-H373-H302
May damage fertility or the unborn child.
Suspected of causing genetic defects.
May cause damage to organs through prolonged or repeated exposure.
Harmful if swallowed.
P201-P202-P261-P264b-P270-P271-P280i-P281-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P362-P501c
H301-H312+H332-H315-H319-H335-H341-H361d
DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber : 200-085-6
RTECSNumber : YR0350000
TSCA : Yes
storageNote1 : Air Sensitive
Recommended Storage : Ambient temperatures
RUO – Research Use Only