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5-Bromo-2'-deoxyuridine, 99%, Thermo Scientific Chemicals
$79.70 - $635.71
Chemical Identifiers
CAS | 59-14-3 |
---|---|
Molecular Formula | C9H11BrN2O5 |
Molecular Weight (g/mol) | 307.10 |
MDL Number | MFCD00006529 |
InChI Key | WOVKYSAHUYNSMH-RRKCRQDMSA-N |
Synonym | 5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine |
PubChem CID | 6035 |
ChEBI | CHEBI:472552 |
IUPAC Name | 5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O |
Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
AAH27260MD
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Thermo Scientific Chemicals
H27260MD |
250 mg |
Each for $79.70
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AAH2726003
|
Thermo Scientific Chemicals
H2726003 |
1 g |
Each for $202.92
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AAH2726006
|
Thermo Scientific Chemicals
H2726006 |
5 g |
Each for $635.71
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Description
5-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Chemical Identifiers
59-14-3 | |
307.10 | |
WOVKYSAHUYNSMH-RRKCRQDMSA-N | |
6035 | |
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
C9H11BrN2O5 | |
MFCD00006529 | |
5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine | |
CHEBI:472552 | |
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O |
Specifications
59-14-3 | |
C9H11BrN2O5 | |
250 mg | |
14,1452 | |
Soluble in water. | |
+31° (c=1 in 0.1N HCl) | |
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione | |
6035 | |
307.1 | |
5-Bromo-2'-deoxyuridine |
∽190°C (decomposition) | |
MFCD00006529 | |
30395 | |
5-bromo-2'-deoxyuridine, broxuridine, bromodeoxyuridine, brdu, 5-bromodeoxyuridine, 5-brdu, budr, 5-bromouracil deoxyriboside, bromouracil deoxyriboside, 5-bromodesoxyuridine | |
WOVKYSAHUYNSMH-RRKCRQDMSA-N | |
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O | |
307.10 | |
CHEBI:472552 | |
99% |
Safety and Handling
GHS H Statement
H341
Suspected of causing genetic defects.
P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
H315-H319-H335-H341
EINECSNumber : 200-415-9
RTECSNumber : YU7350000
TSCA : Yes
Recommended Storage : Keep cold
RUO – Research Use Only