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  6. Thermo Scientific™ 5-Azacytidine, 99%

Thermo Scientific™ 5-Azacytidine, 99%

5-Azacytidine, CAS # 320-67-2, is an chemical analog of cytidine that acts as an inhibitor of DNA methyltransferase activity.

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Chemical Identifiers

CAS 320-67-2
Molecular Formula C8H12N4O5
Molecular Weight (g/mol) 244.21
MDL Number MFCD00006539
InChI Key NMUSYJAQQFHJEW-KVTDHHQDSA-N
Synonym 5-azacitidine, 5-azacytidine, azacitidina, azacitidine, azacitidinum, azacitidinum inn-latin, azacytidine, ladakamycin, mylosar, vidaza
PubChem CID 9444
ChEBI CHEBI:2038
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
SMILES C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AC226620500
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Thermo Scientific™
226620500 		50mg
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AC226620010
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Thermo Scientific™
226620010 		1g
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Description

Description

This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description
5-Azacytidine is a chemical analog of the nucleoside cytidine that incorporates into DNA and inhibits DNA methylation
At low doses, 5-azacytidine irreversibly binds the enzyme DNA methyltransferase (DNMT)
Applications
5-Azacytidine has been used for cardiomyocyte differentiation from mesenchymal stem cells
It has been used as a potent DNMT inhibitor in the study of tumor cell proliferation and induction of gene expression following demethylation
5-Azacytidine can globally change histone modification patterns
Specifications

Chemical Identifiers

320-67-2
244.21
NMUSYJAQQFHJEW-KVTDHHQDSA-N
9444
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
C8H12N4O5
MFCD00006539
5-azacitidine, 5-azacytidine, azacitidina, azacitidine, azacitidinum, azacitidinum inn-latin, azacytidine, ladakamycin, mylosar, vidaza
CHEBI:2038
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N

Specifications

320-67-2
100.0
228.0°C to 230.0°C
C8H12N4O5
MFCD00006539
15, 884
5-azacitidine, 5-azacytidine, azacitidina, azacitidine, azacitidinum, azacitidinum inn-latin, azacytidine, ladakamycin, mylosar, vidaza
NMUSYJAQQFHJEW-KVTDHHQDSA-N
+ 40.00
244.21
CHEBI:2038
Crystalline Powder
5-Azacytidine, 99%
98.5
White
98.5% min. (HPLC)
Authentic
Glass bottle
50mg
Solubility in water: .. Other solubilities: soluble in methanol
C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
9444
244.21
99%
Safety and Handling

Safety and Handling

GHS H Statement
Harmful if swallowed.
May cause genetic defects.
May cause cancer.

GHS P Statement
IF SWALLOWED: rinse mouth.
Do NOT induce vomiting.
Call a POISON CENTER or doctor/physician if you feel unwell.
Wash face,hands and any exposed skin thoroughly after handling.
Obtain special instructions before us

GHS Signal Word: Danger

EINECSNumber : 206-280-2

RTECSNumber : XZ3017500

SDS
Product Certifications

RUO – Research Use Only