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5-Azacytidine, 98%, Thermo Scientific Chemicals
Causes DNA demethylation or hemi-demethylation; a powerful mutagen
$126.92 - $489.22
Chemical Identifiers
| CAS | 320-67-2 |
|---|---|
| Molecular Formula | C8H12N4O5 |
| Molecular Weight (g/mol) | 244.21 |
| MDL Number | MFCD00006539 |
| InChI Key | NMUSYJAQQFHJEW-KVTDHHQDSA-N |
| Synonym | 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin |
| PubChem CID | 9444 |
| ChEBI | CHEBI:2038 |
| IUPAC Name | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one |
| SMILES | NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6415903
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Thermo Scientific Chemicals
J6415903 |
1 g |
N/A
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AAJ6415906
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Thermo Scientific Chemicals
J6415906 |
5 g |
N/A
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Description
5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.
Solubility
Soluble in water.
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Chemical Identifiers
| 320-67-2 | |
| 244.21 | |
| NMUSYJAQQFHJEW-KVTDHHQDSA-N | |
| 9444 | |
| 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one |
| C8H12N4O5 | |
| MFCD00006539 | |
| 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin | |
| CHEBI:2038 | |
| NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
Specifications
| 320-67-2 | |
| White | |
| MFCD00006539 | |
| 620461 | |
| 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin | |
| NMUSYJAQQFHJEW-KVTDHHQDSA-N | |
| 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one | |
| 9444 | |
| 244.2 | |
| Powder |
| 226°C to 232°C (decomposition) | |
| C8H12N4O5 | |
| 1 g | |
| 14,890 | |
| Soluble in water. | |
| NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O | |
| 244.21 | |
| CHEBI:2038 | |
| 98% | |
| 5-Azacytidine |
Safety and Handling
GHS H Statement
H340-H350-H302
May cause genetic defects.
May cause cancer.
Harmful if swallowed.
P201-P202-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
H302-H340-H350
EINECSNumber : 206-280-2
RTECSNumber : XZ3017500
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only