missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Alfa Aesar™ 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside, 98%

Activator of AMP-activated protein kinase (AMPK)

$174.26 - $459.55

Chemical Identifiers

CAS 2627-69-2
Molecular Formula C9H14N4O5
Molecular Weight (g/mol) 258.234
MDL Number MFCD00869751
InChI Key RTRQQBHATOEIAF-UUOKFMHZSA-N
Synonym acadesine, aica-riboside, aicar, arasine, aica riboside, aic-riboside, acadesina, acadesinum, 5-amino-1-beta-d-ribofuranosyl-1h-imidazole-4-carboxamide, protara
PubChem CID 17513
ChEBI CHEBI:28498
IUPAC Name 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
SMILES C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ64720MF View Documents Alfa Aesar™
J64720MF
50mg Each for $174.26
 
AAJ64720EX3 View Documents Alfa Aesar™
J64720EX3
200mg Each for $459.55
 
Description

Description

Applications
5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

Solubility
Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at less than 1mg/ml

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Specifications

Chemical Identifiers

2627-69-2
258.234
RTRQQBHATOEIAF-UUOKFMHZSA-N
17513
5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
C9H14N4O5
MFCD00869751
acadesine, aica-riboside, aicar, arasine, aica riboside, aic-riboside, acadesina, acadesinum, 5-amino-1-beta-d-ribofuranosyl-1h-imidazole-4-carboxamide, protara
CHEBI:28498
C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N

Specifications

Brown
50mg
C9H14N4O5
14,16
Soluble in DMSO at 2mg/ml; Soluble in water or ethanol at less than 1mg/ml
C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
258.234
CHEBI:28498
Powder
5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside
214°C to 215°C
2627-69-2
MFCD00869751
acadesine, aica-riboside, aicar, arasine, aica riboside, aic-riboside, acadesina, acadesinum, 5-amino-1-beta-d-ribofuranosyl-1h-imidazole-4-carboxamide, protara
RTRQQBHATOEIAF-UUOKFMHZSA-N
5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
17513
258.23
98%
Safety and Handling

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

TSCA : TSCA

Recommended Storage : −30° to −10°C