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Alfa Aesar™ 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside, 98%

Activator of AMP-activated protein kinase (AMPK)

$441.27 - $441.27

Chemical Identifiers

Chemical Name or Material 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside
CAS 2627-69-2
Molecular Formula C9H14N4O5
Formula Weight 258.23g/mol
MDL Number MFCD00869751
Merck Index 14,16
Synonym Acadesine; AICAR
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ64720EX3

 
alfa aesar™
J64720-EX3
200mg Each for $441.27
Description & Specifications

Specifications

Melting Point 214° to 215°C
Color Pale Brown
Quantity 200mg
Chemical Name or Material 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside
CAS 2627-69-2
Physical Form Powder
Assay 98%
Molecular Formula C9H14N4O5
Formula Weight 258.23g/mol
MDL Number MFCD00869751
Merck Index 14,16
Synonym Acadesine; AICAR
Solubility Information Soluble in DMSO at 2mg/ml; Soluble in water or ethanol at less than 1mg/ml
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage −30° to −10°C
TSCA TSCA

Applications
5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

Solubility
Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at less than 1mg/ml

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

−30° to −10°C