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4-Thiouridine, 98+% Alfa Aesar™

$618.39 - $618.39

Chemical Identifiers

CAS 13957-31-8
Molecular Formula C9H12N2O5S
Molecular Weight (g/mol) 260.264
MDL Number MFCD00006538
InChI Key ZLOIGESWDJYCTF-XVFCMESISA-N
Synonym 4-thiouridine, thiouridine, uridine, 4-thio, 1-beta-d-ribofuranosyl-4-thiouracil, 1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one, 1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one, s4u, thiouridine van, uridine,4-thio, 4-thio-d-uridine
PubChem CID 3032615
ChEBI CHEBI:20480
IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one
SMILES C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ60679MC View Documents Alfa Aesar
J60679MC
100mg Each for $618.39
 
Description

Description

Applications
4-Thiouridine is a constituent of several transfer RNA′s. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.

Solubility
Soluble in water (20 mg/ml), and methanol (10 mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.
Specifications

Chemical Identifiers

13957-31-8
260.264
ZLOIGESWDJYCTF-XVFCMESISA-N
3032615
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one
C9H12N2O5S
MFCD00006538
4-thiouridine, thiouridine, uridine, 4-thio, 1-beta-d-ribofuranosyl-4-thiouracil, 1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one, 1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one, s4u, thiouridine van, uridine,4-thio, 4-thio-d-uridine
CHEBI:20480
C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O

Specifications

Yellow
13957-31-8
MFCD00006538
ZLOIGESWDJYCTF-XVFCMESISA-N
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one
3032615
260.27
≥98%
100mg
C9H12N2O5S
4-thiouridine, thiouridine, uridine, 4-thio, 1-beta-d-ribofuranosyl-4-thiouracil, 1-2r,3r,4s,5r-3,4-dihydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-4-thioxo-3,4-dihydropyrimidin-2 1h-one, 1-beta-d-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2 1h-one, s4u, thiouridine van, uridine,4-thio, 4-thio-d-uridine
C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O
260.264
CHEBI:20480
Crystalline
4-Thiouridine
Safety and Handling

Safety and Handling

Recommended Storage : −30° to −10°C