4-Methoxy-o-phenylenediamine is widely used as an intermediate in organic synthesis and pharmaceuticals. It is an important precursor for the synthesis of other heterocyclic compounds. It is used in the determination of glyoxal, methylglyoxal, and diacetyl in urine using 4-methoxy-o-phenylenediamine as derivatizing reagent by High-performance liquid chromatography (HPLC).
Soluble in water.
Store in a cool place. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. Hygroscopic.
Safety and Handling
GHS H Statement
Harmful if swallowed.
Harmful in contact with skin.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
GHS P Statement
Wear protective gloves/clothing.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.