4,5-Dicyanoimidazole is used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis, and synthesis of nucleoside phosphoramidites, synthesis of novel nucleosides. It is often used as an alternative to tetrazole.
Soluble in Acetonitrile: 1.8g/10ml, DMSO, Methanol.
Store in a cool, dry conditions in well sealed container. Incompatible with oxidizing agents.
|173° to 177°C|
Safety and Handling
GHS H Statement
Causes serious eye damage.
Harmful if swallowed.
May cause respiratory irritation.
Causes skin irritation.
GHS P Statement
Wear protective gloves/clothing.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.