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4',5,7-Trihydroxyflavone, 97%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals L15041MB
Description
4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
Solubility
Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.
Specifications
| 4',5,7-Trihydroxyflavone | |
| ∽315°C (decomposition) | |
| MFCD00006831 | |
| 262620 | |
| apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone | |
| KZNIFHPLKGYRTM-UHFFFAOYSA-N | |
| 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one | |
| 5280443 | |
| 270.24 |
| 520-36-5 | |
| C15H10O5 | |
| 25 mg | |
| 14,730 | |
| Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml). | |
| OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1 | |
| 270.24 | |
| CHEBI:18388 | |
| 97% |
Chemical Identifiers
| 520-36-5 | |
| 270.24 | |
| KZNIFHPLKGYRTM-UHFFFAOYSA-N | |
| 5280443 | |
| 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one |
| C15H10O5 | |
| MFCD00006831 | |
| apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone | |
| CHEBI:18388 | |
| OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1 |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 208-292-3
RTECSNumber : LK9276000
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only