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Alfa Aesar™ 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

Chemical Identifiers

Chemical Name or Material 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
CAS 30827-99-7
Molecular Formula C8H10FNO2S·HCl
Formula Weight 239.69g/mol
MDL Number MFCD00132962
UN Number UN3261
Beilstein 7604627
Synonym AEBSF
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAH2647303

 
alfa aesar™
H26473-03
1g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAH26473MD

 
alfa aesar™
H26473-MD
250mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Melting Point ≈184°C (dec.)
Quantity 1g
Chemical Name or Material 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
CAS 30827-99-7
Assay 97%
Molecular Formula C8H10FNO2S·HCl
Formula Weight 239.69g/mol
MDL Number MFCD00132962
UN Number UN3261
Beilstein 7604627
Synonym AEBSF
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
Health Hazard 3 GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage −30° to −10°C
DOT Information Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.

Applications
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.

Solubility
Soluble in water 50 mg/mL or 100% ethanol.

Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.

Safety and Handling

Danger

GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

−30° to −10°C