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Alfa Aesar™ 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%

Chemical Identifiers

Chemical Name or Material 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
CAS 30827-99-7
Molecular Formula C8H10FNO2S·HCl
Formula Weight 239.69
MDL Number MFCD00132962
UN Number UN3261
Beilstein 7604627
Synonym AEBSF
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAH2647303

  SDS
alfa aesar™
H2647303
1g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAH26473MD

  SDS
alfa aesar™
H26473MD
250mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Formula Weight 239.69
Quantity 1g
Health Hazard 2 GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
MDL Number MFCD00132962
Assay 97%
Beilstein 7604627
UN Number UN3261
Health Hazard 3 GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Health Hazard 1 Danger
Melting Point ≈184°C (dec.)
Chemical Name or Material 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
Molecular Formula C8H10FNO2S·HCl
Synonym AEBSF
CAS 30827-99-7
DOT Information Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
Recommended Storage −30° to −10°C

Applications
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.

Solubility
Soluble in water 50 mg/mL or 100% ethanol.

Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.

Safety and Handling

Danger

GHS P Statement
P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.

−30° to −10°C