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3,4-Diaminopyridine, 97%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A1246506
Description
It is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsIt is a potassium channel blocker in nerve terminals. It inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.
Solubility
Soluble in water (24 mg/ml at 20°C), alcohol. Slightly soluble in ether.
Notes
Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.
Specifications
| 3,4-Diaminopyridine | |
| 217°C to 220°C | |
| Unpleasant | |
| MFCD00006401 | |
| UN2811 | |
| 14,2986 | |
| Soluble in water (24mg/ml at 20°C),alcohol. Slightly soluble in ether. | |
| C1=CN=CC(=C1N)N | |
| 109.132 | |
| 109.13 |
| 54-96-6 | |
| 240°C (464°F) | |
| C5H7N3 | |
| 5 g | |
| 110232 | |
| 3,4-diaminopyridine, amifampridine, 3,4-pyridinediamine, firdapse, diamino-3,4 pyridine, 4,5-diaminopyridine, 3,4-dap, amifampridin, zenas, pyridine, 3,4-diamino | |
| OYTKINVCDFNREN-UHFFFAOYSA-N | |
| pyridine-3,4-diamine | |
| 5918 | |
| ≥98% |
Chemical Identifiers
| 54-96-6 | |
| 109.132 | |
| OYTKINVCDFNREN-UHFFFAOYSA-N | |
| 5918 | |
| C1=CN=CC(=C1N)N |
| C5H7N3 | |
| MFCD00006401 | |
| 3,4-diaminopyridine, amifampridine, 3,4-pyridinediamine, firdapse, diamino-3,4 pyridine, 4,5-diaminopyridine, 3,4-dap, amifampridin, zenas, pyridine, 3,4-diamino | |
| pyridine-3,4-diamine |
Safety and Handling
GHS H Statement
H300-H330-H312-H319
Fatal if swallowed.
Fatal if inhaled.
Harmful in contact with skin.
Causes serious eye irritation.
P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P361-P363-P501c
H300+H330-H311-H315-H318-H335
DOTInformation : Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber : 200-220-9
RTECSNumber : US7600000
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only