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Alfa Aesar™ 3,3',5-Triiodo-L-thyronine, 95%

$89.34 - $857.76

Chemical Identifiers

Chemical Name or Material 3,3',5-Triiodo-L-thyronine
CAS 6893-02-3
Molecular Formula C15H12I3NO4
Formula Weight 650.97g/mol
MDL Number MFCD00002593
Synonym O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAH3406803

 
alfa aesar™
H34068-03
1g Each for $284.49

AAH3406806

 
alfa aesar™
H34068-06
5g Each for $857.76

AAH34068MD

 
alfa aesar™
H34068-MD
250mg Each for $89.34
Description & Specifications

Specifications

Melting Point 234° to 238°C
Quantity 1g
Optical Rotation +25° (c=1 in 1M HCl/Ethanol 1:2)
Chemical Name or Material 3,3',5-Triiodo-L-thyronine
CAS 6893-02-3
Assay 95%
Molecular Formula C15H12I3NO4
Formula Weight 650.97g/mol
MDL Number MFCD00002593
Synonym O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; Liothyronine
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECS Number AY6750000

Applications
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3′, 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3′, 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3′-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3′,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.

Solubility
Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.