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2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%
CAS: 105832-38-0 | C9H16BF4N3O3 | 301.05 g/mol
Supplier: Thermo Scientific Chemicals L1353814
Description
2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.
Solubility
Soluble in acetonitrile, DMF, chloroform, dichlorormethane and acetonitrile.
Notes
Moisture sensitive, Incompatible with strong oxidizing agents.
Specifications
| 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate | |
| 195°C to 200°C | |
| MFCD00077875 | |
| Moisture sensitive | |
| Soluble in acetonitrile,DMF,chloroform,dichlorormethane and acetonitrile. | |
| F[B-](F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C | |
| 301.05 | |
| 301.05 |
| 105832-38-0 | |
| C9H16BF4N3O3 | |
| 25 g | |
| tstu, o-n-succinimidyl-1,1,3,3-tetramethyluronium tetrafluoroborate, 2-2,5-dioxopyrrolidin-1-yl-1,1,3,3-tetramethylisouronium tetrafluoroborate, 2-succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, n,n,n',n'-tetramethyl-o-n-succinimidyl uronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyluronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl-uronium tetrafluoroborate, dimethylamino 2,5-dioxopyrrolidin-1-yl oxy methylidene dimethylazanium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl uronium bf4, pubchem12781 | |
| YEBLHMRPZHNTEK-UHFFFAOYSA-N | |
| [dimethylamino-(2,5-dioxopyrrolidin-1-yl)oxymethylidene]-dimethylazanium;tetrafluoroborate | |
| 9857522 | |
| 98% |
Chemical Identifiers
| 105832-38-0 | |
| 301.05 | |
| YEBLHMRPZHNTEK-UHFFFAOYSA-N | |
| 9857522 | |
| F[B-](F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C |
| C9H16BF4N3O3 | |
| MFCD00077875 | |
| tstu, o-n-succinimidyl-1,1,3,3-tetramethyluronium tetrafluoroborate, 2-2,5-dioxopyrrolidin-1-yl-1,1,3,3-tetramethylisouronium tetrafluoroborate, 2-succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, n,n,n',n'-tetramethyl-o-n-succinimidyl uronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyluronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl-uronium tetrafluoroborate, dimethylamino 2,5-dioxopyrrolidin-1-yl oxy methylidene dimethylazanium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl uronium bf4, pubchem12781 | |
| [dimethylamino-(2,5-dioxopyrrolidin-1-yl)oxymethylidene]-dimethylazanium;tetrafluoroborate |
Safety and Handling
GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 000-000-0
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only