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2-Mercaptoethanol, Electrophoresis Grade, 98+%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals J6674230
Description
β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applicationsβ-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.
Solubility
Fully miscible in water. Soluble in alcohol, ether, benzene, and other organic solvents.
Notes
Handle under dry protective gas. Store in cool condition. Incompatible with air, moisture, oxidizing agents.
Specifications
2-Mercaptoethanol | |
-100°C | |
1.114 g/mL | |
73°C (163°F) | |
C2H6OS | |
MFCD00004890 | |
UN2966 | |
Air sensitive; Hygroscopic | |
2-mercaptoethanol, mercaptoethanol, thioglycol, beta-mercaptoethanol, ethanol, 2-mercapto, 2-thioethanol, 2-hydroxy-1-ethanethiol, thioethylene glycol, 2-hydroxyethanethiol, 2-hydroxyethyl mercaptan | |
DGVVWUTYPXICAM-UHFFFAOYSA-N | |
2-sulfanylethanol | |
1567 | |
78.13 | |
Electrophoresis |
60-24-2 | |
Colorless | |
156°C to 158°C | |
Unpleasant | |
HSCH2CH2OH | |
250 g | |
773648 | |
14,5869 | |
Fully miscible in water. Soluble in alcohol,ether,benzene,and other organic solvents. | |
OCCS | |
78.13 | |
CHEBI:41218 | |
≥98% | |
Liquid |
Chemical Identifiers
60-24-2 | |
78.13 | |
DGVVWUTYPXICAM-UHFFFAOYSA-N | |
1567 | |
OCCS |
C2H6OS | |
MFCD00004890 | |
2-mercaptoethanol, mercaptoethanol, thioglycol, beta-mercaptoethanol, ethanol, 2-mercapto, 2-thioethanol, 2-hydroxy-1-ethanethiol, thioethylene glycol, 2-hydroxyethanethiol, 2-hydroxyethyl mercaptan | |
CHEBI:41218 |
Safety and Handling
GHS H Statement
H301-H310-H318-H227-H315-H317-H335
Toxic if swallowed.
Fatal in contact with skin.
Causes serious eye damage.
Combustible liquid.
Causes skin irritation.
May cause an allergic skin reaction.
May cause respiratory irritation.
P210-P235-P260-P262-P264b-P270-P271-P272-P280-P301+P310-P302+P350-P304+P340-P305+P351+P338-P310-P311-P314-P330-P333+P313-P361-P363-P370+P378q-P501c
H227-H301+H331-H310-H315-H317-H318-H373
DOTInformation : Transport Hazard Class: 6.1; Packaging Group: II; Proper Shipping Name: THIOGLYCOL
EINECSNumber : 200-464-6
RTECSNumber : KL5600000
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only