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Alfa Aesar™ 17-(Allylamino)-17-demethoxygeldanamycin, 99%


Possesses anti-tumor activity

Quantity 200mg

Manufacturer: alfa aesar™  J66960-EX3

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Catalog No. AAJ66960EX3

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Description & Specifications

Chemical Identifiers

Quantity 200mg
Melting Point 207 to 209°C
Quantity 200mg
Sensitivity Light Sensitive
Chemical Name or Material 17-(Allylamino)-17-demethoxygeldanamycin
CAS 75747-14-7
Physical Form Solid
Assay 99%
Molecular Formula C31H43N3O8
Formula Weight 585.69g/mol
MDL Number MFCD04973892
Synonym 17-AAG; 17-(Allylamino)geldanamycin
Solubility Information Soluble in DMSO at 150mg/mL; soluble in ethanol at 5mg/mL; Very poorly soluble in water
Storage Note 1 -30° to -10°C
Recommended Storage −30° to −10°C
RTECS Number LX8932000

Specifications

Chemical Name or Material 17-(Allylamino)-17-demethoxygeldanamycin
CAS 75747-14-7
Molecular Formula C31H43N3O8
Formula Weight 585.69g/mol
MDL Number MFCD04973892
Synonym 17-AAG; 17-(Allylamino)geldanamycin

Applications
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis.

Solubility
Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/mL. Very poorly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Accessories

−30° to −10°C

-30° to -10°C