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Thermo Scientific™ Lab Vision™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody


Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1185P1ABX

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Catalog No. MS1185P1ABX

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Description & Specifications

Specifications

Antigen 14.3.3sigma Ab-1
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 1433S01
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Murine
Immunogen Recombinant human 1433 sigma protein
Isotype IgG2a kappa
Quantity 100μL
Regulatory Status RUO
Research Discipline Signal Transduction
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody.

14.3.3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14.3.3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14.3.3 and target proteins are strongly influenced by the phosphorylation state of 14.3.3 and the target protein. 14.3.3 σ shares cyclin-Cdk2 binding motifs with different cell cycle regulators, including p107, p130, p21Cip1, p27Kip1, and p57Kip2 and is associated with cyclin-Cdk complexes in vitro and in vivo.

Host Species: Mouse

Clone: 1433S01

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant human 14.3.3σ protein

Molecular Weight: 26-30kDa

Positive Control: HT29 cells, Skin

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO