Thermo Scientific™ Lab Vision™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody
Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1185PABX
Take advantage of a quality product that delivers accurate results with the Thermo Scientific™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody.14.3.3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14.3.3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14.3.3 and target proteins are strongly influenced by the phosphorylation state of 14.3.3 and the target protein. 14.3.3 σ shares cyclin-Cdk2 binding motifs with different cell cycle regulators, including p107, p130, p21Cip1, p27Kip1, and p57Kip2 and is associated with cyclin-Cdk complexes in vitro and in vivo.
Host Species: Mouse
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant human 14.3.3σ protein
Molecular Weight: 26-30kDa
Positive Control: HT29 cells, Skin
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Ab without BSA/Azide (Frozen)|
|Recombinant human 1433 sigma protein|
|Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blotting|