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Alfa Aesar™ 1-Trimethylsilylmethanol, 98+%

Chemical Identifiers

Chemical Name or Material 1-Trimethylsilylmethanol
CAS 3219-63-4
Molecular Formula (CH3)3SiCH2OH
Formula Weight 104.23
MDL Number MFCD00004596
UN Number UN1993
Beilstein 1731486
Synonym (Hydroxymethyl)trimethylsilane
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAL0425103

  SDS
alfa aesar™
L0425103
1g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.

AAL0425106

  SDS
alfa aesar™
L0425106
5g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Formula Weight 104.23
Chemical Name or Material 1-Trimethylsilylmethanol
Assay ≥98%
Molecular Formula (CH3)3SiCH2OH
MDL Number MFCD00004596
CAS 3219-63-4
UN Number UN1993
Health Hazard 3 GHS P Statement
P210-P280-P240-P303+P361+P353-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Wear protective gloves/protective clothing/eye protection/face protection.
Ground/bond container and receiving equipment.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
Store in a well-ventilated place. Keep cool.
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECS Number PC4100000
Flash Point 31°C (87°F)
TSCA TSCA
Health Hazard 1 Warning
Synonym (Hydroxymethyl)trimethylsilane
Quantity 1g
Beilstein 1731486
Boiling Point 121° to 122°C
DOT Information Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
Health Hazard 2 GHS H Statement
H226
Flammable liquid and vapor.

Applications
1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Solubility
Fully miscible in water.

Notes
Store at 4°C. Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Safety and Handling

Warning

GHS P Statement
P210-P280-P240-P303+P361+P353-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Wear protective gloves/protective clothing/eye protection/face protection.
Ground/bond container and receiving equipment.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
Store in a well-ventilated place. Keep cool.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H226
Flammable liquid and vapor.