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1-Methylpiperazine, 98+%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A10837AP
Description
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
Solubility
Miscible with water and methanol.
Notes
Hygroscopic. Moisture sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
Specifications
1-Methylpiperazine | |
-6°C | |
137°C to 139°C | |
Amine-like | |
1.4655 | |
500 mL | |
102724 | |
n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine | |
PVOAHINGSUIXLS-UHFFFAOYSA-N | |
1-methylpiperazine | |
53167 | |
≥98% |
109-01-3 | |
0.903 | |
34°C (93°F) | |
C5H12N2 | |
MFCD00005966 | |
UN2734 | |
Air Sensitive | |
Miscible with water and methanol. | |
CN1CCNCC1 | |
100.165 | |
100.17 |
Chemical Identifiers
109-01-3 | |
100.165 | |
PVOAHINGSUIXLS-UHFFFAOYSA-N | |
53167 | |
CN1CCNCC1 |
C5H12N2 | |
MFCD00005966 | |
n-methylpiperazine, piperazine, 1-methyl, 4-methylpiperazine, 1-methyl-piperazine, n-methyl piperazine, 1-methyl piperazine, methylpiperazine, n-methyl-piperazine, n-methylpiperazin, 1-methylpyperazine | |
1-methylpiperazine |
Safety and Handling
GHS H Statement
H331-H314-H318-H226-H302-H312
Toxic if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if swallowed.
Harmful in contact with skin.
P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c
H226-H302+H312+H332-H314-H317-H335
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: AMINES, LIQUID, CORROSIVE, FLAMMABLE, N.O.S.
EINECSNumber : 203-639-5
RTECSNumber : TM1225000
TSCA : Yes
Recommended Storage : Ambient temperatures; Store under Argon
RUO – Research Use Only