1-Bromo-1-chloro-2,2,2-trifluoroethane has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. It is also used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor. In an effect believed to be independent of anesthesia, halothane inhibits synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.
Soluble in water (8 mg/ml).
Light Sensitive. Store in the dark. Store away from oxidizing agents. Incompatible with light and oxidizing agents.
|49° to 50°C|
Safety and Handling
GHS H Statement
Causes serious eye damage.
Suspected of causing genetic defects.
GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
Use personal protective equipment as required.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
RTECSNumber : KH6550000
Recommended Storage : 2° to 8°C