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1-Boc-piperazine, 99%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals L1336314
Description
1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.
Solubility
Soluble in ethyl acetate, methanol and water.
Notes
Hygroscopic. Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
Specifications
| 1-Boc-piperazine | |
| 44°C to 48°C | |
| MFCD00075265 | |
| 879985 | |
| 1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester | |
| CWXPZXBSDSIRCS-UHFFFAOYSA-O | |
| tert-butyl piperazine-1-carboxylate | |
| 143452 | |
| 99% |
| 57260-71-6 | |
| C9H19N2O2 | |
| 25 g | |
| Air Sensitive | |
| Soluble in ethyl acetate,methanol and water. | |
| CC(C)(C)OC(=O)N1CC[NH2+]CC1 | |
| 187.26 | |
| 186.26 |
Chemical Identifiers
| 57260-71-6 | |
| 187.26 | |
| CWXPZXBSDSIRCS-UHFFFAOYSA-O | |
| 143452 | |
| CC(C)(C)OC(=O)N1CC[NH2+]CC1 |
| C9H19N2O2 | |
| MFCD00075265 | |
| 1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester | |
| tert-butyl piperazine-1-carboxylate |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
TSCA : No
Recommended Storage : Ambient temperatures; Store under Nitrogen
RUO – Research Use Only