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Thermo Scientific™ Lab Vision™ α -1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody

Obtain accurate, reproducible results with Thermo Scientific™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody.

$330.90 - $695.45

Specifications

Antigen alpha-1-Antitrypsin Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Baboon
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

RB367A

 
thermo scientific™ lab vision™
RB-367-A
1mL Each for $695.45

RB367A1

 
thermo scientific™ lab vision™
RB-367-A1
500µL Each for $450.76

RB367R7

 
thermo scientific™ lab vision™
RB-367-R7
7mL Each for $330.90
Description & Specifications

Specifications

Antigen alpha-1-Antitrypsin Ab-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Baboon
Cross Reactivity Equine
Cross Reactivity Human
Cross Reactivity Mink
Cross Reactivity Baboon
Cross Reactivity Equine
Cross Reactivity Human
Cross Reactivity Mink
Cross Reactivity Baboon
Cross Reactivity Equine
Cross Reactivity Human
Cross Reactivity Mink
Cross Reactivity Baboon
Cross Reactivity Equine
Cross Reactivity Human
Cross Reactivity Mink
Host Species Rabbit
Regulatory Status RUO
Research Discipline Enzyme
Type Primary
Immunogen Purified human serum alpha-1-AT
Isotype IgG

Obtain accurate, reproducible results with Thermo Scientific™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody. This antibody detects alpha-1-antitrypsin (alpha-1-AT), which exists in a number of genetic variants of which MM variant is the most common.

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Baboon, Monkey, Horse and Mink. Does not react with cow, kangaroo, pig, goat, sheep, cat, dog, guinea pig, mouse and chicken. Others not known.

Immunogen: Purified human serum α-1-AT

Positive Control: Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

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