Learn More
1,1'-Carbonyldiimidazole, 97%, Thermo Scientific Chemicals
Supplier: Thermo Scientific Chemicals A1468818
Description
Peptide coupling reagent1,1'-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohols and amines into carbamates, esters, and ureas. It is involved in the preparation of formylized imidazole by reaction with formic acid. Further, it is used in the synthesis of dipolar polyamides compounds. In addition to this, it is considered as an equivalent of phosgene and used to prepare asymmetric bis alkyl carbonate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsPeptide coupling reagent1,1′-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohols and amines into carbamates, esters, and ureas. It is involved in the preparation of formylized imidazole by reaction with formic acid. Further, it is used in the synthesis of dipolar polyamides compounds. In addition to this, it is considered as an equivalent of phosgene and used to prepare asymmetric bis alkyl carbonate.
Solubility
Soluble in dimethylformamide.
Notes
Store in a cool place. Incompatible with water, strong acids, strong oxidizing agents, strong bases and amines.
Specifications
N, N'-Carbonyldiimidazole | |
116°C to 120°C | |
C7H6N4O | |
50 g | |
6826 | |
14,1819 | |
Soluble in dimethylformamide. | |
O=C(N1C=CN=C1)N1C=CN=C1 | |
162.15 | |
162.15 |
530-62-1 | |
97% | |
MFCD00005286 | |
UN3263 | |
Moisture sensitive | |
1,1'-carbonyldiimidazole, n,n'-carbonyldiimidazole, carbonyldiimidazole, di 1h-imidazol-1-yl methanone, n,n-carbonyldiimidazole, 1h-imidazole, 1,1'-carbonylbis, 1,1'-carbonylbis-1h-imidazole, carbonyl diimidazole, diimidazol-1-yl ketone, 1,1-carbonyldiimidazole | |
PFKFTWBEEFSNDU-UHFFFAOYSA-N | |
1-(1H-imidazole-1-carbonyl)-1H-imidazole | |
68263 | |
97% |
Chemical Identifiers
530-62-1 | |
162.15 | |
PFKFTWBEEFSNDU-UHFFFAOYSA-N | |
68263 |
C7H6N4O | |
MFCD00005286 | |
1,1'-carbonyldiimidazole, n,n'-carbonyldiimidazole, carbonyldiimidazole, di 1h-imidazol-1-yl methanone, n,n-carbonyldiimidazole, 1h-imidazole, 1,1'-carbonylbis, 1,1'-carbonylbis-1h-imidazole, carbonyl diimidazole, diimidazol-1-yl ketone, 1,1-carbonyldiimidazole | |
O=C(N1C=CN=C1)N1C=CN=C1 |
Safety and Handling
GHS H Statement
H314-H318-H302
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
H302-H314-H335
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.
EINECSNumber : 208-488-9
TSCA : Yes
storageNote1 : Moisture sensitive
Recommended Storage : Ambient temperatures; Store under Argon
RUO – Research Use Only