Alfa Aesar™ 1,1,3,3-Tetramethylguanidine, 99%
Manufacturer: Alfa Aesar™ A12314AP
1,1,3,3-Tetramethylguanidine is employed as a polyurethane foam catalyst, as an accelerator for the syntheses of polysulfured rubber. It is also used as a strong base in the photochemical (couplers) and in the pharmaceutical (steroids) industries. It is essential for the preparation of alkyl nitriles from alkyl halides and 3′-alkylthymidines from 3′-nitrothymidines. It serves as an efficient and selective catalyst for the benzoylation of alcohols. It replaces the expensive bases 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) in organic synthesis.
Miscible with water.
Air sensitive. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Keep away from sources of ignition.
Safety and Handling
GHS H Statement
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if swallowed.
GHS P Statement
Keep away from heat/sparks/open flames/hot surfaces.
- No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.
TSCA : TSCA