CD63, clone: Ts63, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Life Technologies LS10628D
CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas.
|CD63 Monoclonal Antibody, 200μL, 0.5mg/mL Concentration, Ts63 Clone, CD63 Antigen, Jurkat and HeLa (human cell lines) Immunogen, Mouse Host, Human Reactivity, Unconjugated, IgG1 Isotype, Used For Western blot|
|PBS with 0.09% sodium azide; pH 7.4|
|LAMP-3, ME491, MLA1, OMA81H, TSPAN30|
|RUOþFor research use only|
|Western BlotþWestern blot|
|Jurkat and HeLa (human cell lines), Jurkat and HeLa (human cell lines)|
|30 to 60kDa|
|4° C, 4°C|
|0.09% Sodium azide|
For Research Use Only. Not for use in diagnostic procedures.