Cytiva HyClone™ Fetal Bovine Serum (U.S.), Dialyzed

Description

Augment growth of cells with U.S.-sourced HyClone™ Dialyzed Fetal Bovine Serum (FBS), depleted of small molecules (less than 10,000 MW) and filtered through sequential 100nm (0.1μm) pore-size rated filters.

Used in applications requiring serum depleted from low-molecular weight components of less than Mr 10 000

The serum is subjected to dialysis through a diafiltration process that reduces concentrations of small molecules such as nucleotides and amino acids that are necessary for alternative biochemical survival pathways

The process reduces hypoxanthine and thymidine concentrations below detectable levels

While producing the same results, a major difference between diafiltration and traditional dialysis is that the driving force for diafiltration is hydrostatic pressure, rather than the concentration gradient for traditional dialysis

Monitoring glucose concentrations carefully controls the diafiltration process

The glucose concentration, which is representative of the extent of dialysis, is reported for each lot of serum