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Genlantis™ PrimaPure™ Human Aortic Endothelial Cells (HAOEC) and Kits

Functionally characterized

Manufacturer:  Genlantis PH30405AK

Catalog No. PH30405AK



Description

Description

Human Aortic Endothelial Cells (HAOEC) are primary endothelial cells isolated from normal human aorta. They are cryopreserved at second passage and can be cultured and propagated at least 16 population doublings. They respond to cytokine stimulation by expressing cell adhesion molecules. Aortic endothelial cells have been used as an in vitro model for the study of morphological and ultra-structural changes1 in the development of atherosclerosis. HAOEC system has also been used for the study of endothelial cell-dependent lymphocyte activation2 and chemoattractant activity for lymphocytes3 in relation to the degree of atherosclerosis.

  • Each lot functionally characterized
  • Single donors to allow variability comparisons
  • Each lot tested negative for HIV, Hepatitis B & C, mycoplasma, bacteria, yeast, and fungi
  • Performance guaranteed with Genlantis media and reagents

REFERENCES:
1. Antonor, A.S. et al, Atherosclerosis 59:1 (1986).
2. Ashida, E.R. et al, J. Clin. Invest. 67:1490 (1981).
3. Farber, H.W. et al, Amer. J. Physiol. 262 (4 parts): H1088 (1992).

†Each kit contains an ampule of cryopreserved HAOEC (PH30405A), 500mL of Endothelial Cell Growth Medium (PM211500), and a Subculture Reagent Kit (PR090100K).

Specifications

Specifications

Used as an in-vitro model for the study of morphological and ultra-structural changes in the development of atherosclerosis, for the study of endothelial cell-dependent lymphocyte activation and chemoattractant activity for lymphocytes
Endothelial Cell Growth Medium
Normal Human Aorta
1 Kit
One ampoule of cryopreserved HAOEC, 500mL endothelial cell growth medium, a subculture reagent kit (100mL each of HEPES buffered saline solution, trypsin/EDTA, and trypsin neutralizing solution)
16 Population Doublings
Human Aortic Endothelial Cells (Adult)
4° and -20°C
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